From Conception to Birth: A Life Unfolds
by Alexander Tsiaras
from Doubleday
The splendor and beauty of a child’s growth and development in the womb--seen through unforgettable images made possible by revolutionary advances in visualization technology
What’s happening with the baby now? All expectant parents ask this question throughout the exhilirating months of pregnancy. Fuzzy sonograms and doctor’s explanations can provide basic information, but through Alexander Tsiaras’ remarkable achievements in medical imaging technology, parents can see, for the first time, the awe-inspiring process of a new life unfolding, in stunning, vivid detail.
The milestones of pregnancy which before could only be described can now be witnessed: the heart’s first beats; the appearance of color in the eye; the emergence of toes and teeth; the brain and nervous system directing development; the first movement of tiny legs and arms; the first indications of gender; the wondrous symbiosis of mother and child; the symphony of the body’s systems coming into being and working in concert. The book tracks the development of a baby from the moment of conception, through the explosively complex early stages of development and the amazing stages of growth as the baby is nurtured by the mother, ending with the joy of birth.
All this is made possible by revolutions in two sciences. As biologists have decoded the molecular basis of life, computer scientists have developed non-invasive, three-dimensional techniques for visualizing the body. Alexander Tsiaras has been a pioneer in merging these explorations and discoveries. He has created a virtual camera studio that enables him to view a human body or any part of it individually, scan it, enlarge it, rotate it, adjust its transparency so that we can view inside a living being, and light it from any angle. The result is an ability to illuminate the unseen elements that make us who we are, and the miraculous images in From Conception to Birth.
Developmental Biology, Eighth Edition (Developmental Biology)
by Scott F. Gilbert
from Sinauer Associates Inc.
The Eighth Edition of Developmental Biology expands its coverage of the mechanisms of development, the roles that environmental factors play in development, the medical applications of our knowledge of development, and the roles that development plays in evolution, highlighting all the incredible advances that have been made in the last three years. Written primarily for undergraduate biology majors, it also serves to introduce graduate students and medical students to developmental biology.
A completely updated text integrates classical developmental biology with contemporary techniques, including new material on: stem cells niches; microRNAs; sperm-egg attraction and binding; induction and maintenance of pluripotency; pioneer transcription factors and the recruitment of nucleosome remodeling proteins; left-right gene expression asymmetry; heart chamber specification; neural crest cell specification and differentiation; somite formation; human brain growth genes; the syndetome; new sources of muscle precursor cells; newly discovered mechanisms of teratogenesis; the effects of endocrine disruptors on human development; sex determination pathways in the brain; the effects of maternal nutrition on gene expression and disease susceptibility in the adult offspring; controversies over digit specification in birds and dinosaurs and whether mammalian blastomere fate is biased at the first division; and much more. Included with every copy of the book is Vade Mecum2: An Interactive Guide to Developmental Biology. In addition to a wealth of interactive content, this updated version includes a new Teachers' and Student's Resource with PowerPoint® slides of chick whole mounts and serial sections. A searchable PDF file on the CD contains full citations for the book's literature cited, with links to PubMed. The CD also includes Mary Tyler's laboratory manual, Developmental Biology: A Guide for Experimental Study, Third Edition, in electronic (PDF) format. textbook and provides more information for advanced students, historical, philosophical, and ethical perspectives on issues in developmental biology, movies, interviews, Web links, and updates. The website includes the full bibliography of literature cited in the book (over 5,000 references), most of which are linked to their PubMed citations.
Endless Forms Most Beautiful: The New Science of Evo Devo
by Sean B. Carroll
from W. W. Norton
"Every animal form is the product of two processes--development from an egg and evolution from its ancestors," writes Sean B. Carroll in his introduction to Endless Forms Most Beautiful. The new science of "evo devo"--or evolutionary developmental biology--examines the relationships between those two processes, embryonic development and evolutionary changes, despite their radically different time scales. Carroll first offers a recap of how genes express themselves in a growing embryo, then peers into the life histories of real-life examples to explain how those genes have changed (or not changed) over millions of years of evolution. Paraphrasing Thomas Huxley, he asks us to consider evolution and development as two sides of the same coin.
We may marvel at the process of an egg becoming an adult, but we accept it as an everyday fact. It is merely then a lack of imagination to fail to grasp how changes in this process that assimilated over long periods of time, far longer than the span of human experience, shape life's diversity."The book's second half is where Carroll really gets at the meat of evo devo, explaining how regulatory genes control such mysteries as individual and population changes in butterfly's spots, jaguar fur, and hominid skulls. Evo devo is one of the hottest areas of study in 21st-century biology, and Carroll's outline of the field is a great place to start understanding it. --Therese Littleton
"A beautiful and very important book."—Lewis Wolpert, American Scientist
For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo—Evolutionary Developmental Biology—is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.
Perhaps the most surprising finding of Evo Devo is the discovery that a small number of primitive genes led to the formation of fundamental organs and appendages in all animal forms. The gene that causes humans to form arms and legs is the same gene that causes birds and insects to form wings, and fish to form fins; similarly, one ancient gene has led to the creation of eyes across the animal kingdom. Changes in the way this ancient tool kit of genes is used have created all the diversity that surrounds us.
Sean Carroll is the ideal author to lead the curious on this intellectual adventure—he is the acknowledged leader of the field, and his seminal discoveries have been featured in Time and The New York Times. 16 pages of color and 100 black-and-white illustrations.
The Primal Teen: What the New Discoveries about the Teenage Brain Tell Us about Our Kids
by Barbara Strauch
from Anchor
For anyone who has ever puzzled over the mysterious and often infuriating behavior of a teenager comes a groundbreaking look at the teenage brain written by the medical science and health editor for The New York Times. While many members of the scientific community have long held that the growing pains of adolescence are primarily psychological, Barbara Strauch highlights the physical nature of the transformation, offering parents and educators a new perspective on erratic teenage behavior. Using plain language, Strauch draws upon the latest scientific discoveries to make the case that the changes the brain goes through during adolescence are as dramatic and crucial as those that take place in the first two years of life, and that teenagers are not entirely responsible for their sullen, rebellious, and moody ways. Featuring interviews with scientists, teenagers, parents, and teachers, The Primal Teen explores common challenges–why teens go from articulate and mature one day to morose and unreachable the next, why they engage in risky behavior–and offers practical strategies to help manage these formative and often difficult years.
Freaks of Nature: What Anomalies Tell Us About Development and Evolution
by Mark S. Blumberg
from Oxford University Press, USA
In most respects, Abigail and Brittany Hensel are normal American twins. Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.
In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a "freak," but a limbless reptile-a snake-a successful variation?
What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.
In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.
Consciousness: A Very Short Introduction (Very Short Introductions)
by Susan Blackmore
from Oxford University Press, USA
"The last great mystery for science," consciousness has become a controversial topic. Consciousness: A Very Short Introduction challenges readers to reconsider key concepts such as personality, free will, and the soul. How can a physical brain create our experience of the world? What creates our identity? Do we really have free will? Could consciousness itself be an illusion? Exciting new developments in brain science are opening up these debates, and the field has now expanded to include biologists, neuroscientists, psychologists, and philosophers. This book clarifies the potentially confusing arguments and clearly describes the major theories, with illustrations and lively cartoons to help explain the experiments. Topics include vision and attention, theories of self, experiments on action and awareness, altered states of consciousness, and the effects of brain damage and drugs. This lively, engaging, and authoritative book provides a clear overview of the subject that combines the perspectives of philosophy, psychology, and neuroscience--and serves as a much-needed launch pad for further exploration of this complicated and unsolved issue.
On Growth and Form
by D'Arcy Wentworth Thompson
from Cambridge University Press
First published in 1917, On Growth and Form was at once revolutionary and conservative. Scottish embryologist D'Arcy Wentworth Thompson (1860-1948) grew up in the newly cast shadow of Darwinism, and he took issue with some of the orthodoxies of the day--not because they were necessarily wrong, he said, but because they violated the spirit of Occam's razor, in which simple explanations are preferable to complex ones. In the case of such subjects as the growth of eggs, skeletons, and crystals, Thompson cited mathematical authority: these were matters of "economy and transformation," and they could be explained by laws governing surface tension and the like. (He doubtless would have enjoyed the study of fractals, which came after his time.) In On Growth and Form, he examines such matters as the curve of frequency or bell curve (which explains variations in height among 10-year-old schoolboys, the florets of a daisy, the distribution of darts on a cork board, the thickness of stripes along a zebra's flanks, the shape of mountain ranges and sand dunes) and spirals (which turn up everywhere in nature you look: in the curve of a seashell, the swirl of water boiling in a saucepan, the sweep of faraway nebulae, the twist of a strand of DNA, the turns of the labyrinth in which the legendary Minotaur lived out its days). The result is an astonishingly varied book that repays skimming and close reading alike. English biologist Sir Peter Medawar called Thompson's tome "beyond comparison the finest work of literature in all the annals of science that have been recorded in the English tongue." --Gregory McNamee
Why do living things and physical phenomena take the form they do? D'Arcy Thompson's classic On Growth and Form looks at the way things grow and the shapes they take. Analysing biological processes in their mathematical and physical aspects, this historic work, first published in 1917, has also become renowned for the sheer poetry of its descriptions. A great scientist sensitive to the fascinations and beauty of the natural world tells of jumping fleas and slipper limpets; of buds and seeds; of bees' cells and rain drops; of the potter's thumb and the spider's web; of a film of soap and a bubble of oil; of a splash of a pebble in a pond. D'Arcy Thompson's writing, hailed as 'good literature as well as good science; a discourse on science as though it were a humanity', is now made available for a wider readership, with a foreword by one of today's great populisers of science, explaining the importance of the work for a new generation of readers.
Why do living things and physical phenomena take the forms they do? Analyzing the mathematical and physical aspects of biological processes, this historic work, first published in 1917, has become renowned as well for the poetry of is descriptions.
Principles of Development
by Lewis Wolpert
from Oxford University Press, USA
Completely updated and revised in a new edition, Principles of Development presents major principles and concepts in the field for an undergraduate audience. Emphasizing gene control as the key to understanding development, the third edition is written in accessible prose, utilizing an impressive art program - 650 full color figures - as well as summaries and diagrams throughout the text to illuminate conceptually challenging material. In addition, the third edition presents carefully selected articles for further reading that expound on principles covered in the text.
The Design of Life: Discovering Signs of Intelligence In Biological Systems
by William A. Dembski
from Foundation for Thought and Ethics
"The illusion of purpose is so powerful," writes Richard Dawkins, "that biologists themselves use the assumption of good design as a working tool." As an ardent proponent of Darwinian evolution, Dawkins imagines that all design in biology is merely an illusion. By contrast, this book shows that biologists use the assumption of design with success precisely because design in biology is not an illusion but real. In this book, William Dembski and Jonathan Wells present a compelling scientific case for the intelligent design of biological systems. Their laser-like analysis, clear explanations, and brilliant analogies will captivate every reader, whether trained scientist or curious layperson. Intelligent design (ID), as the study of patterns in nature best explained by intelligence, is already accepted in many special sciences. Archeology, forensics, and the Search for Extraterrestrial Intelligence (SETI) all belong to ID in this broad sense. These sciences, however, are uncontroversial because any intelligence there could be an "evolved" intelligence. In biology, by contrast, intelligent design is highly controversial because any intelligence there would be an "unevolved" intelligence - it would not be the product of purely material evolutionary processes. Thus, to convinced materialists like Richard Dawkins, who dogmatically accept Darwinian orthodoxy, this book comes as a shot across the bow. Scientists who support the intelligent design of biological systems are routinely held up to ridicule, stripped of their status, denied tenure, and driven from their posts. Why? They do not agree that the universe, life, and the human mind are the accidental outworking of purely material forces. And why don't they agree? Because the evidence of science shows otherwise. This book presents that evidence clearly and cogently. Written for the general reader, it will quickly enter the national conversation. In The Design of Life, Dembski and Wells make the most powerful and comprehensive case to date for the intelligent design of life. This is the book that the promoters of unintelligent evolution do NOT want you to read.
"The illusion of purpose is so powerful," writes Richard Dawkins, "that biologists themselves use the assumption of good design as a working tool." As an ardent proponent of Darwinian evolution, Dawkins imagines that all design in biology is merely an illusion. By contrast, this book shows that biologists use the assumption of design with success precisely because design in biology is not an illusion but real. In this book, William Dembski and Jonathan Wells present a compelling scientific case for the intelligent design of biological systems. Their laser-like analysis, clear explanations, and brilliant analogies will captivate every reader, whether trained scientist or curious layperson. Intelligent design (ID), as the study of patterns in nature best explained by intelligence, is already accepted in many special sciences. Archeology, forensics, and the Search for Extraterrestrial Intelligence (SETI) all belong to ID in this broad sense. These sciences, however, are uncontroversial because any intelligence there could be an "evolved" intelligence. In biology, by contrast, intelligent design is highly controversial because any intelligence there would be an "unevolved" intelligence - it would not be the product of purely material evolutionary processes. Thus, to convinced materialists like Richard Dawkins, who dogmatically accept Darwinian orthodoxy, this book comes as a shot across the bow. Scientists who support the intelligent design of biological systems are routinely held up to ridicule, stripped of their status, denied tenure, and driven from their posts. Why? They do not agree that the universe, life, and the human mind are the accidental outworking of purely material forces. And why don't they agree? Because the evidence of science shows otherwise. This book presents that evidence clearly and cogently. Written for the general reader, it will quickly enter the national conversation. In The Design of Life, Dembski and Wells make the most powerful and comprehensive case to date for the intelligent design of life. This is the book that the promoters of unintelligent evolution do NOT want you to read.
The Symbolic Species: The Co-Evolution of Language and the Brain
by Terrence W. Deacon
from W. W. Norton & Company
Terrence Deacon's The Symbolic Species begins with a question posed by a 7-year-old child: Why can't animals talk? Or, as Deacon puts it, if animals have simpler brains, why can't they develop a simpler form of language to go with them? Thus begins the basic line of inquiry for this breathtakingly ambitious work, which attempts to describe the origins of human language and consciousness.
What separates humans from animals, Deacon writes, is our capacity for symbolic representation. Animals can easily learn to link a sound with an object or an effect with a cause. But symbolic thinking assumes the ability to associate things that might only rarely have a physical correlation; think of the word "unicorn," for instance, or the idea of the future. Language is only the outward expression of this symbolic ability, which lays the foundation for everything from human laughter to our compulsive search for meaning.
The final section of The Symbolic Species posits that human brains and human language have coevolved over millions of years, leading Deacon to the remarkable conclusion that many modern human traits were actually caused by ideas. Deacon's background in biological anthropology and neuroscience makes him a reliable companion through this complicated multidisciplinary turf. Rigorously researched and argued in dense but lively prose, The Symbolic Species is that rare animal, a book of serious science that's accessible to layman and scientist alike.
This revolutionary book provides fresh answers to long-standing questions of human origins and consciousness. Drawing on his breakthrough research in comparative neuroscience, Terrence Deacon offers a wealth of insights into the significance of symbolic thinking: from the co-evolutionary exchange between language and brains over two million years of hominid evolution to the ethical repercussions that followed man's newfound access to other people's thoughts and emotions. Informing these insights is a new understanding of how Darwinian processes underlie the brain's development and function as well as its evolution. In contrast to much contemporary neuroscience that treats the brain as no more or less than a computer, Deacon provides a new clarity of vision into the mechanism of mind. It injects a renewed sense of adventure into the experience of being human.
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