Biotechnology

The Singularity Is Near: When Humans Transcend Biology

For over three decades, Ray Kurzweil has been one of the most respected and provocative advocates of the role of technology in our future. In his classic The Age of Spiritual Machines, he argued that computers would soon rival the full range of human intelligence at its best. Now he examines the next step in this inexorable evolutionary process: the union of human and machine, in which the knowledge and skills embedded in our brains will be combined with the vastly greater capacity, speed, and knowledge-sharing ability of our creations.

Microcosm: E. coli and the New Science of Life

•Within days of being born, we are infected with billions of E. coli. They will inhabit each and every one of us until we die. E. coli is notorious for making people gravely ill, but engineered strains of the bacteria save millions of lives each year.

•Despite its microscopic size, E.coli contains more than four thousand genes that operate a staggeringly sophisticated network of millions of molecules.

•Scientists are rebuilding E. coli from the ground up, redefining our understanding of life on Earth.

In the tradition of classics like Lewis Thomas's Lives of a Cell, Carl Zimmer has written a fascinating and utterly accessible investigation of what it means to be alive. Zimmer traces E. coli's remarkable history, showing how scientists used it to discover how genes work and then to launch the entire biotechnology industry. While some strains of E. coli grab headlines by causing deadly diseases, scientists are retooling the bacteria to produce everything from human insulin to jet fuel.

Microcosm is the story of the one species on Earth that science knows best of all. It's also a story of life itself--of its rules, its mysteries, and its future.

Biomimicry: Innovation Inspired by Nature

This profound and accessible book details how science is studying nature's best ideas to solve our toughest 21st–century problems.

If chaos theory transformed our view of the universe, biomimicry is transforming our life on Earth. Biomimicry is innovation inspired by nature – taking advantage of evolution's 3.8 billion years of R\'9126D since the first bacteria. Biomimics study nature's best ideas: photosynthesis, brain power, and shells – and adapt them for human use. They are revolutionising how we invent, compute, heal ourselves, harness energy, repair the environment, and feed the world.

Science writer and lecturer Janine Benyus names and explains this phenomenon. She takes us into the lab and out in the field with cutting–edge researchers as they stir vats of proteins to unleash their computing power; analyse how electrons zipping around a leaf cell convert sunlight into fuel in trillionths of a second; discover miracle drugs by watching what chimps eat when theyᱥ sick; study the hardy prairie as a model for low–maintenance agriculture; and more.

Fantastic Voyage: Live Long Enough to Live Forever

The idea behind Kurzweil and Grossman's Fantastic Voyage is that if you can make it through the next 50 years, you might become immortal. How will that be possible? Through some rather science fictional steps, it turns out, including taking advantage of the latest in biotechnological breakthroughs and not-yet-invented nanotechnology. Is all this longing for immortality driven by an obsession with youth or a fear of death? Readers can judge for themselves, as both Kurzweil and Grossman reveal the personal histories that led them to develop this plan. Fantastic Voyage is written in an easy-to-understand tone, with lots of sidebars giving examples of what the future holds for medicine and health. Whether or not you think that science will find a way to keep our bodies or our disembodied minds alive forever, this book is full of diet and lifestyle tips. For instance, the authors suggest carefully controlling the body's overall pH at an alkaline level, meditating, eating a diet composed mostly of vegetables and protein, and taking loads of supplements (Kurzweil downs about 250 pills each day). The dietary options presented here will mostly only be practical for people whose income levels can support buying organic produce, fresh fish and meat, and top-shelf supplements. The authors cavalierly state that we are living in a "time of abundance," but it seems likely that most who are able to follow this regimen will be Americans of a fairly high socioeconomic class. --Therese Littleton

Tap todayÂ’s technological breakthroughs to live longer and better.

Startling discoveries in the areas of genomics, biotechnology, and nanotechnology occur practically every day. The rewards of this research, some of it as spectacular as science fiction, are practically in our grasp. Fantastic Voyage shows us how we can use these new technologies to live longer than previously imaginable.

The authors take the reader on a journey to undreamed-of vitality with a comprehensive investigation into the cutting-edge science regarding diet, supplementation, genetics, detoxification, and the hormones involved with aging and youth. By following their program, which includes such simple recommendations as eating a balanced, low- glycemic-index diet, and taking powerful anti-aging nutritional supplements, anyone will be able to add years of healthy, active life.

Genome: The Autobiography of a Species in 23 Chapters (P.S.)

Science writer Matt Ridley has found a way to tell someone else's story without being accused of plagiarism. Genome: The Autobiography of a Species in 23 Chapters delves deep within your body (and, to be fair, Ridley's too) looking for dirt dug up by the Human Genome Project. Each chapter pries one gene out of its chromosome and focuses on its role in our development and adult life, but also goes further, exploring the implications of genetic research and our quickly changing social attitudes toward this information. Genome shies away from the "tedious biochemical middle managers" that only a nerd could love and instead goes for the A-material: genes associated with cancer, intelligence, sex (of course), and more.

Readers unfamiliar with the jargon of genetic research needn't fear; Ridley provides a quick, clear guide to the few words and concepts he must use to translate hard science into English. His writing is informal, relaxed, and playful, guiding the reader so effortlessly through our 23 chromosomes that by the end we wish we had more. He believes that the Human Genome Project will be as world-changing as the splitting of the atom; if so, he is helping us prepare for exciting times--the hope of a cure for cancer contrasts starkly with the horrors of newly empowered eugenicists. Anyone interested in the future of the body should get a head start with the clever, engrossing Genome. --Rob Lightner

Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life.

Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Seeds of Destruction: The Hidden Agenda of Genetic Manipulation

This skillfully researched book focuses on how a small socio-political American elite seeks to establish its control over the very basis of human survival, the provision of our daily bread. Control the food and you control the people. This is no ordinary book about the perils of GMO. Engdahl takes the reader inside the corridors of power, into the backrooms of the science labs, behind closed doors in the corporate boardrooms. The author reveals a World of profit-driven political intrigue, government corruption and coercion, where genetic manipulation and the patenting of life forms are used to gain worldwide control over food production. The book is an eye-opener, a must-read for all those committed to the causes of social justice and World peace.

Molecular Biology of the Cell, Fourth Edition

Molecular Biology of the Cell is the classic in-depth text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown.
The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice.

Prentice Hall Health's Question and Answer Review of Medical Technology/Clinical Laboratory Science (3rd Edition) (Prentice Hall SUCCESS! Series)

Science Business: The Promise, the Reality, and the Future of Biotech

Why has the biotechnology industry failed to perform up to expectations—despite all its promise? In Science Business, Gary P. Pisano answers this question by providing an incisive critique of the industry. Pisano not only reveals the underlying causes of biotech’s problems; he offers the most sophisticated analysis yet on how the industry works. And he provides clear prescriptions for companies, investors, and policymakers seeking ways to improve the industry’s performance.

According to Pisano, the biotech industry’s problems stem from its special character as a science-based business. This character poses three unique business challenges: 1) how to finance highly risky investments under profound uncertainty and long time horizons for R&D, 2) how to learn rapidly enough to keep pace with advances in drug science knowledge, and 3) how to integrate capabilities across a broad spectrum of scientific and technological knowledge bases.

The key to fixing the industry? Business models, organizational structures, and financing arrangements that place greater emphasis on integration and long-term learning over shorter-term “monetization” of intellectual property. Pisano maintains that all industry players—biotech firms, investors, universities, pharmaceutical companies, government regulators—can play a role in righting the industry. The payoff? Valuable improvements in health care, and a shinier future for human well-being.

Bioinformatics For Dummies (For Dummies (Math & Science))

Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop!

Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:

• Analyze all types of sequences
• Use all types of databases
• Work with DNA and protein sequences
• Conduct similarity searches
• Build a multiple sequence alignment
• Edit and publish alignments
• Visualize protein 3-D structures
• Construct phylogenetic trees

This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you’ll be searching databases and analyzing sequences like a pro!